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An inhaler or puffer is a medical device to deliver precise doses of pharmaceuticals directly to the lungs. They are commonly used for persons who suffer from asthma, COPD, severe bronchitis and pulmonary fibrosis. In most cases, the drug delivered is a steroid.

There are several different types of inhalers

For lung diseases, delivering medication directly to the lungs is necessary as the bloodstream does not penetrate directly into the air sacs of the lungs - in other words nothing in the blood apart from gases like oxygen and carbon dioxide is allowed through the membrane separating the two sides of the air sac. Even molecules as small as water generally cannot penetrate the barrier.

In Pilot, Gregory House is perturbed when a mother has not been letting her asthmatic son use his inhaler because of her fear of steroids.

In Joy to the World, House is desperately trying to be nice to a clinic patient when she demonstrates her inhaler by pointing it at her neck and activating it.

Inhaler at Wikipedia